The use of bone turnover markers in chronic kidney disease-mineral and bone disorders

Osteoporosis in mineral and bone disorders of chronic kidney disease.

Osteoporosis is one of the epidemics in modern aging societies. Epidemiological studies indicate that many patients with osteoporosis are also characterized by diminished glomerular filtration rate (GFR), which indicates various degrees of chronic kidney disease (CKD). On the other hand, the status of osteoporosis in the classification of mineral and bone disorders in CKD has not been well defi...

Chronic Kidney Disease-Mineral and Bone Disorder

1Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan 2Centre for Nephrology & Urology, Department of Physiology, Shenzhen University Health Science Center, Shenzhen, China 3Centre for Nephrology, University College London, London, UK 4Centre for Cardiovascular Science, Queen’s Medical Re...

The New Kidney and Bone Disease: Chronic Kidney Disease – Mineral and Bone Disorder (CKD–MBD)

Kidney is one of the most important organs in the regulation of mineral metabolism (Fukagawa et al., 2006). Chronic kidney disease (CKD) is a worldwide public health problem that affects 5% to 10% of the world population, with increasing prevalence and adverse outcomes, including progressive loss of kidney function, cardiovascular disease, and premature death (Eknoyan et al., 2004). Calcium and...

Bone and mineral disorders after kidney transplantation.

Chronic kidney disease-mineral and bone disorder KDIGO guidelines.

• one measure of the skeletal component of the systemic disorder of CKD-MBD that is quantifiable by histomorphometry of bone biopsy. The guidelines themselves focussed on three key domains relating to: (1) diagnosis of CKD-MBD with respect to biochemical abnormalities, bone and vascular calcification, 2009 saw the publication of the clinical practice guidelines from Kidney Disease Improving Glo...